Individually Measured Phenotypes to Advance Computational Translation (IMPACT)

This concept aims to encourage research using novel behavioral measures to foster a new generation of clinical signatures, leading toward precision assessment, prognosis, and treatment of mental disorders. The initial focus will be to (1) develop or optimize behavioral tasks that measure individual differences and demonstrate added utility for clinical prediction when combined with standard clinical diagnosis; (2) form a data infrastructure that can support computational approaches to build tools for clinical decision making. This research will involve one or more longitudinal cohorts established either through new data collection or by leveraging extant cohorts that have appropriate data structures.