Role of T-Cells in HIV Central Nervous System Reservoir Seeding, Persistence, and Neuropathogenesis

The goal of this concept is to encourage research to define the mechanisms and roles of T-cells in HIV/central nervous system (CNS) reservoir seeding, persistence and neuropathogenesis. This research will be critical for developing therapeutic strategies for targeting CNS reservoirs and ongoing neuroinflammation that drive CNS comorbidities.